Archive for October, 2011

How do malignant melanomas cause weight loss in cancer patients?

Sunday, October 23rd, 2011

I read that one of the first signs of cancer is unexplained weight loss. However, I don’t understand how this would happen in something like skin cancer – what has a cancerous mole got to do with your weight and digestive system? Medical explanation, please!

This must be at the late stage of melanoma. Weight loss is not an early symptom/sign of this cancer.

Weight loss can be caused by eating fewer calories, using more calories, or both.

Melanoma at late stage can make chemicals that change the way the body uses certain nutrients, like protein, carbohydrates, and fat. A patient may seem to be eating enough, but the body may not be able to absorb all the nutrients from the food. Tumor selectively use more glucose, so the normal metabolism of the body is no longer there.

For many patients, the effects of cancer and cancer treatments make it hard to eat well. Anorexia and cachexia are common causes of malnutrition in cancer patients.